

| Catalog No. | HT174014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Species reactivity | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human PHYH (Glu56-Leu338). | ||||||||
| Target | PAHX, PhyH, Phytanoyl-CoA alpha-hydroxylase, Phytanic acid oxidase, PHYH, Phytanoyl-CoA dioxygenase, peroxisomal | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | O14832 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Phytanoyl-CoA dioxygenase, peroxisomal (PHYH) is a ~38 kDa protein. Catalyzes the 2-hydroxylation of not only racemic phytanoyl-CoA and the isomers of 3-methylhexadecanoyl-CoA, but also a variety of other mono-branched 3-methylacyl-CoA esters (with a chain length of at least seven carbon atoms) and straight-chain acyl-CoA esters (with a chain length longer than four carbon atoms). Does not hydroxylate long and very long straight chain acyl-CoAs or 2-methyl- and 4-methyl-branched acyl-CoAs. 1. Croes, K. et al. (2000) Journal of lipid research 41, 629-36. PMID: 10744784 2. Mukherji, M. et al. (2002) Chemistry & biology 9, 597-605. PMID: 12031666 3. Foulon, V. et al. (2003) Journal of lipid research 44, 2349-55. PMID: 12923223 4. Mihalik, SJ. et al. (1997) Nature genetics 17, 185-9. PMID: 9326939 | ||||||||
| Note | For research use only. |
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