Anti-Human PIK3CD Polyclonal Antibody (HT068014)

Name: Anti-Human PIK3CD Polyclonal Antibody
Brand: abinScience
SKU: HT068014
Price: 168 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HT068014

Description

Anti-Human PIK3CD Polyclonal Antibody (HT068014) is a rabbit polyclonal antibody detecting PIK3CD. Suitable for Mouse and Human.

Highlights

●Multi-Species — Cross-reactive for translational research.

Species reactivity

Mouse, Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human PIK3CD (Val774-Gln1044).

Target

EC:2.7.1.137, EC:2.7.1.153, PI3-kinase subunit delta, PI3K-delta, PI3Kdelta, PIK3CD, Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform, PtdIns-3-kinase subunit delta, PtdIns-3-kinase subunit p110-delta, p110delta

Endotoxin level

Please contact with the lab for this information.

Purification

Purified by antigen affinity column.

Accession

O00329

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Background

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (PIK3CD) is a ~119 kDa protein. Phosphoinositide-3-kinase (PI3K) phosphorylates phosphatidylinositol (PI) and its phosphorylated derivatives at position 3 of the inositol ring to produce 3-phosphoinositides. Uses ATP and PtdIns(4,5)P2 (phosphatidylinositol 4,5-bisphosphate) to generate phosphatidylinositol 3,4,5-trisphosphate (PIP3). PIP3 plays a key role by recruiting PH domain-containing proteins to the membrane, including AKT1 and PDPK1, activating signaling cascades involved in cell growth, survival, proliferation, motility and morphology. Mediates immune responses. Plays a role in B-cell development, proliferation, migration, and function.

1. Chantry, D. et al. (1997) The Journal of biological chemistry 272, 19236-41. PMID: 9235916

2. Meier, TI. et al. (2004) Protein expression and purification 35, 218-24. PMID: 15135396

Note

For research use only

Images

References

Datasheet

Anti-Human PIK3CD Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human PIK3CD Polyclonal Antibody (HT068014)

Overview

Images

References

Datasheet

SDS

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