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Anti-Human Pinin/PNN/DRSP Polyclonal Antibody (HP977014)

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Overview
Catalog No.HP977014
Species reactivityHuman, Mouse
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human Pinin/PNN/DRSP (Arg123-Arg315).
Target PNN, MEMA, SR-like protein, Nuclear protein SDK3, Domain-rich serine protein, DRSP, 140 kDa nuclear and cell adhesion-related phosphoprotein, Pinin, Desmosome-associated protein, Melanoma metastasis clone A protein, DRS protein, DRS
Purification Purified by antigen affinity column.
Accession Q9H307
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Pinin (PNN/DRSP) is a ~81 kDa protein. Transcriptional activator binding to the E-box 1 core sequence of the E-cadherin promoter gene; the core-binding sequence is 5'CAGGTG-3'. Capable of reversing CTBP1-mediated transcription repression. Auxiliary component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Participates in the regulation of alternative pre-mRNA splicing.

Note For research use only.
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