

| Catalog No. | HF934013 | ||||
|---|---|---|---|---|---|
| Species reactivity | Human | ||||
| Applications | ELISA | ||||
| Host species | Human | ||||
| Isotype | IgG1, kappa | ||||
| Clone ID | SAA2580 | ||||
| Clonality | Monoclonal | ||||
| Target | Alteplase, EC:3.4.21.68, PLAT, Reteplase, Tissue-type plasminogen activator, Tissue-type plasminogen activator chain A, Tissue-type plasminogen activator chain B, t-PA, t-plasminogen activator, tPA | ||||
| Endotoxin level | Please contact with the lab for this information. | ||||
| Purity | >95% as determined by SDS-PAGE. | ||||
| Purification | Protein A/G purified from cell culture supernatant. | ||||
| Accession | P00750 | ||||
| Form | Liquid | ||||
| Storage buffer | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
| ||||
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| Background | Tissue-type plasminogen activator (PLAT) is a ~62 kDa protein. Converts the abundant, but inactive, zymogen plasminogen to plasmin by hydrolyzing a single Arg-Val bond in plasminogen. By controlling plasmin-mediated proteolysis, it plays an important role in tissue remodeling and degradation, in cell migration and many other physiopathological events. During oocyte activation, plays a role in cortical granule reaction in the zona reaction, which contributes to the block to polyspermy. | ||||
| Note | For research use only |




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