Anti-Human PLG/Plasminogen Polyclonal Antibody (HF499014)

Name: Anti-Human PLG/Plasminogen Polyclonal Antibody
Brand: abinScience
SKU: HF499014
Price: 168 USD
Availability: InStock

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HF499014

Description

Anti-Human PLG/Plasminogen Polyclonal Antibody (HF499014) is a rabbit polyclonal antibody detecting Plasminogen in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human PLG/Plasminogen (Val98-Arg580).

Target

Plasminogen, PLG

Purification

Purified by antigen affinity column.

Accession

P00747

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Plasminogen (PLG) is a ~90 kDa protein. Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1, C4 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor.

1. Goldberger, G. et al. (1980) Nature 286, 514-6. PMID: 6447255

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-Human PLG/Plasminogen polyclonal antibody at 1ug/mL on recombinant Human PLG/Plasminogen (Catalog No. HF499022).

References

Datasheet