Anti-Human PLXNB1 Polyclonal Antibody (HT264024)

Name: Anti-Human PLXNB1 Polyclonal Antibody
Brand: abinScience
SKU: HT264024
Price: 168 USD
Availability: InStock

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Datasheet
SDS

Overview

Catalog No.

HT264024

Description

Anti-Human PLXNB1 Polyclonal Antibody (HT264024) is a rabbit polyclonal antibody detecting PLXNB1 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human PLXNB1 (Cys1067-Asp1251).

Target

SEP, Semaphorin receptor SEP, PLXN5, PLXNB1, Plexin-B1, KIAA0407

Purification

Purified by antigen affinity column.

Accession

O43157

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Plexin-B1 (PLXNB1) is a ~232 kDa protein. Receptor for SEMA4D. Plays a role in GABAergic synapse development. Mediates SEMA4A- and SEMA4D-dependent inhibitory synapse development. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration.

1. Tong, Y. et al. (2009) The Journal of biological chemistry 284, 35962-72. PMID: 19843518

2. Janssen, BJ. et al. (2010) Nature 467, 1118-22. PMID: 20877282

3. Bell, CH. et al. (2011) PLoS biology 9, e1001134. PMID: 21912513

4. Aurandt, J. et al. (2002) Proceedings of the National Academy of Sciences of the United States of America 99, 12085-90. PMID: 12196628

5. Swiercz, JM. et al. (2004) The Journal of cell biology 165, 869-80. PMID: 15210733

6. Giordano, S. et al. (2002) Nature cell biology 4, 720-4. PMID: 12198496

Note

For research use only.

Images

References

Datasheet

Anti-Human PLXNB1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human PLXNB1 Polyclonal Antibody (HT264024)

Overview

Images

References

Datasheet

SDS

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