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Anti-Human POU2AF1 Monoclonal Antibody (1A544) (HA822025)

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Anti-Human POU2AF1 Monoclonal Antibody (1A544)
Anti-Human POU2AF1 Monoclonal Antibody (1A544)
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Overview
Catalog No.HA822025
Description
Anti-Human POU2AF1 Monoclonal Antibody (1A544) [1A544] (HA822025) is a mouse monoclonal antibody detecting POU2AF1 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Recombinant — Superior batch-to-batch reproducibility with defined sequences.
  • ●Multi-Application — Validated across multiple applications.
Species reactivityHuman
ApplicationsELISA, IHC, WB
Host speciesMouse
IsotypeIgG
Clone ID1A544
Clonality Monoclonal
Immunogen E. coli - derived recombinant human POU2AF1 (Leu2-Phe256).
Target POU domain class 2-associating factor 1, B-cell-specific coactivator OBF-1, BOB-1, OCA-B, OCT-binding factor 1, POU2AF1
Purification Protein A/G purified from cell culture supernatant.
Accession Q16633
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

POU domain class 2-associating factor 1 (POU2AF1) is a ~27 kDa protein. Transcriptional coactivator that specifically associates with either POU2F1/OCT1 or POU2F2/OCT2. It boosts the POU2F1/OCT1 mediated promoter activity and to a lesser extent, that of POU2F2/OCT2. It recognizes the POU domains of POU2F1/OCT1 and POU2F2/OCT2. It is essential for the response of B-cells to antigens and required for the formation of germinal centers. Regulates IL6 expression in B cells as POU2F2/OCT2 coactivator.

1. Strubin, M. et al. (1995) Cell 80, 497-506. PMID: 7859290
2. Gstaiger, M. et al. (1995) Nature 373, 360-2. PMID: 7779176
3. Luo, Y. et al. (1995) Molecular and cellular biology 15, 4115-24. PMID: 7623806
Note For research use only.
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    SDS-PAGE for Anti-Human POU2AF1 Monoclonal Antibody (1A544)

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Datasheet
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Formula
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