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Anti-Human PRC1 Polyclonal Antibody (HD582014)

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Overview
Catalog No.HD582014
Description
Anti-Human PRC1 Polyclonal Antibody (HD582014) is a rabbit polyclonal antibody detecting PRC1. Suitable for Human.
Species reactivityHuman
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human PRC1 (Met1-Ser466).
Target PRC1, Protein regulator of cytokinesis 1
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession O43663
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

Protein regulator of cytokinesis 1 (PRC1) is a ~71 kDa protein. Key regulator of cytokinesis that cross-links antiparrallel microtubules at an average distance of 35 nM. Essential for controlling the spatiotemporal formation of the midzone and successful cytokinesis. Required for KIF14 localization to the central spindle and midbody. Required to recruit PLK1 to the spindle. Stimulates PLK1 phosphorylation of RACGAP1 to allow recruitment of ECT2 to the central spindle.

1. Kanehira, M. et al. (2007) Cancer research 67, 3276-85. PMID: 17409436
Note For research use only
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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C₁ × V₁ = C₂ × V₂
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C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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C₂ (Working Conc.)
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Anti-Human PRC1 Polyclonal Antibody

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