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Anti-Human PREX2 Polyclonal Antibody (HD162014)

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Overview
Catalog No.HD162014
Description
Anti-Human PREX2 Polyclonal Antibody (HD162014) is a rabbit polyclonal antibody detecting PREX2. Suitable for Human.
Species reactivityHuman
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human PREX2 (Asp880-Val1240).
Target DEP domain-containing protein 2, DEPDC2, P-Rex2, PREX2, Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein, PtdIns(3,4,5)-dependent Rac exchanger 2
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession Q70Z35
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein (PREX2) is a ~182 kDa protein. Functions as a RAC1 guanine nucleotide exchange factor (GEF), activating Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. Mediates the activation of RAC1 in a PI3K-dependent manner. May be an important mediator of Rac signaling, acting directly downstream of both G protein-coupled receptors and phosphoinositide 3-kinase.

Note For research use only
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Formula
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Anti-Human PREX2 Polyclonal Antibody

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