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Anti-Human PRICKLE1 Polyclonal Antibody (HP307014)

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Overview
Catalog No.HP307014
Species reactivityHuman, Mouse, Rat
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human PRICKLE1 (Arg41-Ser327).
Target REST/NRSF-interacting LIM domain protein 1, RILP, PRICKLE1, Prickle-like protein 1
Purification Purified by antigen affinity column.
Accession Q96MT3
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Prickle-like protein 1 (PRICKLE1) is a ~94 kDa protein. Involved in the planar cell polarity pathway that controls convergent extension during gastrulation and neural tube closure. Convergent extension is a complex morphogenetic process during which cells elongate, move mediolaterally, and intercalate between neighboring cells, leading to convergence toward the mediolateral axis and extension along the anteroposterior axis. Necessary for nuclear localization of REST. May serve as nuclear receptor.

Note For research use only.
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Formula
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C₂ (Working Conc.)
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Anti-Human PRICKLE1 Polyclonal Antibody

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