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Anti-Human PSPH Polyclonal Antibody (HX980014)

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Overview
Catalog No.HX980014
Description
Anti-Human PSPH Polyclonal Antibody (HX980014) is a rabbit polyclonal antibody detecting PSPH in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bovine, and Pongo abelii.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Species reactivityHuman, Mouse, Rat
ApplicationsELISA, IHC, WB
Host speciesRabbit
ClonalityPolyclonal
IsotypeIgG
Immunogen E. coli - derived recombinant Human PSPH (Met1-Glu225).
Target O-phosphoserine phosphohydrolase, Phosphoserine phosphatase, L-3-phosphoserine phosphatase, PSP, PSPH, PSPase
Purification Purified by antigen affinity column.
Accession P78330
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Phosphoserine phosphatase (PSPH) is a ~25 kDa protein. Catalyzes the last irreversible step in the biosynthesis of L-serine from carbohydrates, the dephosphorylation of O-phospho-L-serine to L-serine. L-serine can then be used in protein synthesis, to produce other amino acids, in nucleotide metabolism or in glutathione synthesis, or can be racemized to D-serine, a neuromodulator. May also act on O-phospho-D-serine (Probable).

1. Kim, HY. et al. (2002) The Journal of biological chemistry 277, 46651-8. PMID: 12213811
2. Veiga-da-Cunha, M. et al. (2004) European journal of human genetics : EJHG 12, 163-6. PMID: 14673469
3. Peeraer, Y. et al. (2004) European journal of biochemistry 271, 3421-7. PMID: 15291819
4. Vincent, JB. et al. (2015) Clinical genetics 87, 296-8. PMID: 25080166
5. Jaeken, J. et al. (1997) Journal of medical genetics 34, 594-6. PMID: 9222972
Note For research use only.
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Datasheet
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
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Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-Human PSPH Polyclonal Antibody

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