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Anti-Human PTPRN2 Polyclonal Antibody (HV238014)

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Anti-Human PTPRN2 Polyclonal Antibody
Anti-Human PTPRN2 Polyclonal Antibody
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Overview
Catalog No.HV238014
Description
Anti-Human PTPRN2 Polyclonal Antibody (HV238014) is a rabbit polyclonal antibody detecting PTPRN2 in ELISA, IHC, WB. Suitable for Rattus norvegicus, Macaca nemestrina, Mus musculus, and Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Species reactivityHuman, Mouse, Rat
ApplicationsELISA, IHC, WB
Host speciesRabbit
ClonalityPolyclonal
IsotypeIgG
Immunogen E. coli - derived recombinant Human PTPRN2 (Cys839-Gln1015).
Target PTPRN2
Purification Purified by antigen affinity column.
Accession Q92932
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate NamesReceptor-type tyrosine-protein phosphatase N2, R-PTP-N2, 3.1.3.-, 3.1.3.48, Islet cell autoantigen-related protein, IAR, ICAAR, Phogrin, IA-2beta60, PTPRN2, KIAA0387
Background

Receptor-type tyrosine-protein phosphatase N2 (PTPRN2) is a ~111 kDa protein. Plays a role in vesicle-mediated secretory processes. Required for normal accumulation of secretory vesicles in hippocampus, pituitary and pancreatic islets. Required for the accumulation of normal levels of insulin-containing vesicles and preventing their degradation. Plays a role in insulin secretion in response to glucose stimuli. Required for normal accumulation of the neurotransmitters norepinephrine, dopamine and serotonin in the brain.

1. Sengelaub, CA. et al. (2016) The EMBO journal 35, 62-76. PMID: 26620550
Note For research use only.
Images
  • Anti-Human PTPRN2 Polyclonal Antibody

    Western blot

    Western blot analysis was performed using anti-PTPRN2 polyclonal antibody at 1ug/mL on various samples.
    Lane 1: Mouse brain lysate

References
Datasheet
Download SDS PDF
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-Human PTPRN2 Polyclonal Antibody

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