Anti-Human RAB22A Polyclonal Antibody (HP286014)

Name: Anti-Human RAB22A Polyclonal Antibody
Brand: abinScience
SKU: HP286014
Price: 168 USD
Availability: InStock

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Overview

Catalog No.

HP286014

Description

Anti-Human RAB22A Polyclonal Antibody (HP286014) is a rabbit polyclonal antibody detecting RAB22A in ELISA, IHC, WB. Suitable for Human, Mouse, and Dog.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Species reactivity

Human, Mouse

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human RAB22A (Met1-Ala171).

Target

RAB22A, RAB22, Ras-related protein Rab-22A, Rab-22

Purification

Purified by antigen affinity column.

Accession

Q9UL26

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Ras-related protein Rab-22A (RAB22A) is a ~21 kDa protein. The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB22A plays a role in endocytosis and intracellular protein transport. Mediates trafficking of transferrin/TF from early endosomes to recycling endosomes. Required for NGF-mediated endocytosis of NTRK1, and subsequent neurite outgrowth.

1. Magadán, JG. et al. (2006) Molecular and cellular biology 26, 2595-614. PMID: 16537905

2. Wang, L. et al. (2011) Molecular biology of the cell 22, 3853-60. PMID: 21849477

Note

For research use only.

Images

References

Datasheet

Anti-Human RAB22A Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human RAB22A Polyclonal Antibody (HP286014)

Overview

Images

References

Datasheet

SDS

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