Anti-Human RAB39B Monoclonal Antibody (1A444) (HP954025)

Name: Anti-Human RAB39B Monoclonal Antibody (1A444)
Brand: abinScience
SKU: HP954025
Price: 106 USD
Availability: InStock

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Overview

Catalog No.	HP954025
Description	Anti-Human RAB39B Monoclonal Antibody (1A444) [1A444] (HP954025) is a mouse monoclonal antibody detecting RAB39B in ELISA, WB. Suitable for Human. Highlights ●Recombinant — Superior batch-to-batch reproducibility with defined sequences.
Species reactivity	Human
Applications	ELISA, WB
Host species	Mouse
Clonality	Monoclonal
Isotype	IgG1
Clone ID	1A444
Immunogen	Recombinant Human RAB39B protein.
Target	Ras-related protein Rab-39B, RAB39B
Endotoxin level	Please contact with the lab for this information.
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	Q96DA2
Form	Liquid
Storage buffer	0.01M PBS pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background	Ras-related protein Rab-39B (RAB39B) is a ~24 kDa protein. The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB39B is involved in autophagy and may function in autophagosome formation. Binds downstream effector PICK1 to ensure selectively GRIA2 exit from the endoplasmic reticulum to the Golgi and to regulate AMPAR composition at the post-synapses and thus synaptic transmission. May regulate the homeostasis of SNCA/alpha-synuclein. 1. Sellier, C. et al. (2016) The EMBO journal 35, 1276-97. PMID: 27103069 2. Zhang, S. et al. (2023) Nature communications 14, 6360. PMID: 37821429
Note	For research use only.

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SDS-PAGE for Anti-Human RAB39B Monoclonal Antibody (1A444)

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Datasheet

Anti-Human RAB39B Monoclonal Antibody (1A444).pdf

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Anti-Human RAB39B Monoclonal Antibody (1A444) (HP954025)

Overview

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References

Datasheet

SDS