Anti-Human RAB6A Polyclonal Antibody (HB696014)

Name: Anti-Human RAB6A Polyclonal Antibody
Brand: abinScience
SKU: HB696014
Price: 168 USD
Availability: InStock

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Datasheet
SDS

Overview

Catalog No.

HB696014

Species reactivity

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human RAB6A (Arg12-Gly176).

Target

Ras-related protein Rab-6A, Rab-6, RAB6A, RAB6

Purification

Purified by antigen affinity column.

Accession

P20340

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Ras-related protein Rab-6A (RAB6A) is a ~23 kDa protein. The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB6A acts as a regulator of COPI-independent retrograde transport from the Golgi apparatus towards the endoplasmic reticulum (ER). Has a low GTPase activity. Recruits VPS13B to the Golgi membrane.

1. Matsuto, M. et al. (2015) Biochimica et biophysica acta 1853, 2592-609. PMID: 25962623

2. Seifert, W. et al. (2015) The Journal of biological chemistry 290, 3349-58. PMID: 25492866

Note

For research use only.

Images

References

Datasheet

Anti-Human RAB6A Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human RAB6A Polyclonal Antibody (HB696014)

Overview

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References

Datasheet

SDS

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