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Anti-Human RBBP5 IP Recombinant Antibody (SAA0256) (HS761013)

Anti-Human RBBP5 IP Recombinant Antibody (SAA0256)
Anti-Human RBBP5 IP Recombinant Antibody (SAA0256)
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Overview
Catalog No.HS761013
Species reactivityHuman
ApplicationsELISA, IF, IP
Host speciesMouse
IsotypeIgG2a
Clone IDSAA0256
Clonality Monoclonal
Target Retinoblastoma-binding protein 5, Retinoblastoma-binding protein RBQ-3, RBQ3, RBBP-5, RBBP5
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession Q15291
RRID Anti-Human RBBP5 IP Antibody (SAA0256) (abinScience Cat# HS761013, RRID:AB_3729790)
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:2000-1:20000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background

Retinoblastoma-binding protein 5 (RBBP5) is a ~59 kDa protein. In embryonic stem (ES) cells, plays a crucial role in the differentiation potential, particularly along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci, including that mediated by retinoic acid. Does not affect ES cell self-renewal. Component or associated component of some histone methyltransferase complexes which regulates transcription through recruitment of those complexes to gene promoters. As part of the MLL1/MLL complex, involved in mono-, di- and trimethylation at 'Lys-4' of histone H3. Histone H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation.

1. Garapaty, S. et al. (2009) The Journal of biological chemistry 284, 7542-52. PMID: 19131338
2. Patel, A. et al. (2009) The Journal of biological chemistry 284, 24242-56. PMID: 19556245
3. Avdic, V. et al. (2011) Structure (London, England : 1993) 19, 101-8. PMID: 21220120
4. Zhang, P. et al. (2012) Nucleic acids research 40, 4237-46. PMID: 22266653
Note For research use only.
Images
  • Anti-Human RBBP5 IP Recombinant Antibody (SAA0256)

    SDS-PAGE

    SDS-PAGE for Anti-Human RBBP5 IP Antibody (SAA0256)

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
C₁ × V₁ = C₂ × V₂
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Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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