

| Catalog No. | HT344014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human RBFOX2 Polyclonal Antibody (HT344014) is a rabbit polyclonal antibody detecting RBFOX2 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Species reactivity | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human RBFOX2 (Thr119-Ala195). | ||||||||
| Target | RNA binding protein fox-1 homolog 2, Fox-1 homolog B, Hexaribonucleotide-binding protein 2, RNA-binding motif protein 9, RNA-binding protein 9, Repressor of tamoxifen transcriptional activity, RBFOX2, FOX2, HRNBP2, RBM9, RTA | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | O43251 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | RNA binding protein fox-1 homolog 2 (RBFOX2) is a ~41 kDa protein. RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUGU-3' elements. Prevents binding of U2AF2 to the 3'-splice site. Regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis. RNA-binding protein that seems to act as a coregulatory factor of ER-alpha. Together with RNA binding proteins RBPMS and MBNL1/2, activates vascular smooth muscle cells alternative splicing events. 1. Yang, Y. et al. (2023) Nucleic acids research 51, 9961-9982. PMID: 37548402 | ||||||||
| Note | For research use only. |
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