Anti-Human RBM39 Polyclonal Antibody (HC636014)

Name: Anti-Human RBM39 Polyclonal Antibody
Brand: abinScience
SKU: HC636014
Price: 168 USD
Availability: InStock

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SDS

Overview

Catalog No.

HC636014

Species reactivity

Human, Mouse

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human RBM39 (Thr146-Val326).

Target

CAPER alpha, RNA-binding protein 39, RNA-binding region-containing protein 2, CAPERalpha, HCC1, RNPC2, RBM39, RNA-binding motif protein 39, Hepatocellular carcinoma protein 1, Splicing factor HCC1

Purification

Purified by antigen affinity column.

Accession

Q14498

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

RNA-binding protein 39 (RBM39) is a ~59 kDa protein. RNA-binding protein that acts as a pre-mRNA splicing factor. Acts by promoting exon inclusion via regulation of exon cassette splicing. Also acts as a transcriptional coactivator for steroid nuclear receptors ESR1/ER-alpha and ESR2/ER-beta, and JUN/AP-1, independently of the pre-mRNA splicing factor activity.

1. Dowhan, DH. et al. (2005) Molecular cell 17, 429-39. PMID: 15694343

2. Loerch, S. et al. (2014) The Journal of biological chemistry 289, 17325-37. PMID: 24795046

3. Han, T. et al. (2017) Science (New York, N.Y.) 356. PMID: 28302793

4. Uehara, T. et al. (2017) Nature chemical biology 13, 675-680. PMID: 28437394

5. Tari, M. et al. (2019) EMBO reports 20, e47604. PMID: 31271494

Note

For research use only.

Images

References

Datasheet

Anti-Human RBM39 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

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Anti-Human RBM39 Polyclonal Antibody (HC636014)

Overview

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References

Datasheet

SDS

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