

| Catalog No. | HP993014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Species reactivity | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human RILP (Ser21-Gln180). | ||||||||
| Target | Rab-interacting lysosomal protein, RILP | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q96NA2 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Rab-interacting lysosomal protein (RILP) is a ~44 kDa protein. Rab effector playing a role in late endocytic transport to degradative compartments. Involved in the regulation of lysosomal morphology and distribution. Induces recruitment of dynein-dynactin motor complexes to Rab7A-containing late endosome and lysosome compartments. Promotes centripetal migration of phagosomes and the fusion of phagosomes with the late endosomes and lysosomes. 1. Cantalupo, G. et al. (2001) The EMBO journal 20, 683-93. PMID: 11179213 2. Jordens, I. et al. (2001) Current biology : CB 11, 1680-5. PMID: 11696325 3. Harrison, RE. et al. (2003) Molecular and cellular biology 23, 6494-506. PMID: 12944476 4. Wang, T. et al. (2004) Molecular biology of the cell 15, 815-26. PMID: 14668488 5. Starling, GP. et al. (2016) EMBO reports 17, 823-41. PMID: 27113757 | ||||||||
| Note | For research use only. |
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