

| Catalog No. | HA834014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human RNF212 Polyclonal Antibody (HA834014) is a rabbit polyclonal antibody detecting Probable E3 SUMO-protein ligase RNF212; 2.3.2.-; Probable E3 SUMO-protein transferase RNF212; RING finger protein 212; RNF212 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Species reactivity | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant human RNF212 (Met1-Thr139). | ||||||||
| Target | Probable E3 SUMO-protein ligase RNF212; 2.3.2.-; Probable E3 SUMO-protein transferase RNF212; RING finger protein 212; RNF212 | ||||||||
| Endotoxin level | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q495C1 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Probable E3 SUMO-protein ligase RNF212 is a ~33 kDa protein. SUMO E3 ligase that acts as a regulator of crossing-over during meiosis: required to couple chromosome synapsis to the formation of crossover-specific recombination complexes. Localizes to recombination sites and stabilizes meiosis-specific recombination factors, such as MutS-gamma complex proteins (MSH4 and MSH5) and TEX11. May mediate sumoylation of target proteins MSH4 and/or MSH5, leading to enhance their binding to recombination sites. Acts as a limiting factor for crossover designation and/or reinforcement and plays an antagonist role with CCNB1IP1/HEI10 in the regulation of meiotic recombination. | ||||||||
| Note | For research use only |
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