Anti-Human RNF43 Recombinant Antibody (SAA1758) (HP618013)

Name: Anti-Human RNF43 Recombinant Antibody (SAA1758)
Brand: abinScience
SKU: HP618013
Price: 110 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HP618013

Species reactivity

Human

Applications

ELISA, WB

Host species

Mouse

Isotype

IgG2a, kappa

Clone ID

SAA1758

Clonality

Monoclonal

Target

E3 ubiquitin-protein ligase RNF43, RING finger protein 43, RING-type E3 ubiquitin transferase RNF43, RNF43

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q68DV7

RRID

Anti-Human RNF43 Antibody (SAA1758) (abinScience Cat# HP618013, RRID:AB_3727519)

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

E3 ubiquitin-protein ligase RNF43 is a ~85 kDa protein. E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination, endocytosis and subsequent degradation of Wnt receptor complex components Frizzled. Acts on both canonical and non-canonical Wnt signaling pathway. Along with RSPO2 and ZNRF3, constitutes a master switch that governs limb specification.

1. Sugiura, T. et al. (2008) Experimental cell research 314, 1519-28. PMID: 18313049

2. Hao, HX. et al. (2012) Nature 485, 195-200. PMID: 22575959

3. Koo, BK. et al. (2012) Nature 488, 665-9. PMID: 22895187

Note

For research use only.

Isotype Control

Mouse IgG2a (Fc Silence) Recombinant Isotype Control (MOPC 173) (MF533023)

Images

Western blot

Western blot analysis was performed using anti-mouse RNF43 monoclonal antibody at 1ug/mL on various samples.
Lane 1: ATG11865 200ng
Lane 2: negative control

References

Datasheet

Anti-Human RNF43 Recombinant Antibody (SAA1758).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human RNF43 Recombinant Antibody (SAA1758) (HP618013)

Overview

Images

References

Datasheet

SDS

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