

| Catalog No. | HF691014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human RNGTT Polyclonal Antibody (HF691014) is a rabbit polyclonal antibody detecting RNGTT in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Species reactivity | Human, Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human RNGTT (Pro328-Val553). | ||||||||
| Target | mRNA-capping enzyme, HCAP1, HCE, mRNA 5'-triphosphate monophosphatase, 3.6.1.74, mRNA 5'-phosphatase, mRNA guanylyltransferase, 2.7.7.50, GTP--RNA guanylyltransferase, GTase, RNGTT, CAP1A | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | O60942 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | mRNA-capping enzyme (RNGTT) is a ~68 kDa protein. Bifunctional mRNA-capping enzyme exhibiting RNA 5'-triphosphate monophosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the GMP moiety of GTP to the 5'-diphosphate terminus of RNA via a covalent enzyme-GMP reaction intermediate. | ||||||||
| Note | For research use only. |
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