

| Catalog No. | HD580014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human RPA4 Polyclonal Antibody (HD580014) is a rabbit polyclonal antibody detecting RPA4. Suitable for Human.
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| Species reactivity | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human RPA4 (Cys49-Asp261). | ||||||||
| Target | RF-A protein 4, RP-A p30, RPA4, Replication factor A protein 4, Replication protein A 30 kDa subunit | ||||||||
| Endotoxin level | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q13156 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Background | Replication protein A 30 kDa subunit (RPA4) is a ~28 kDa protein. As part of the alternative replication protein A complex, aRPA, binds single-stranded DNA and probably plays a role in DNA repair. Compared to the RPA2-containing, canonical RPA complex, may not support chromosomal DNA replication and cell cycle progression through S-phase. The aRPA may not promote efficient priming by DNA polymerase alpha but could support DNA polymerase delta synthesis in the presence of PCNA and replication factor C (RFC), the dual incision/excision reaction of nucleotide excision repair and RAD51-dependent strand exchange. | ||||||||
| Note | For research use only |
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