

| Catalog No. | HW718014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Species reactivity | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human RPS19 (Met1-His145). | ||||||||
| Target | 40S ribosomal protein S19, Small ribosomal subunit protein eS19, RPS19 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | P39019 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Small ribosomal subunit protein eS19 (RPS19) is a ~16 kDa protein. Component of the small ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Required for pre-rRNA processing and maturation of 40S ribosomal subunits. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. 1. Anger, AM. et al. (2013) Nature 497, 80-5. PMID: 23636399 2. Flygare, J. et al. (2007) Blood 109, 980-6. PMID: 16990592 3. Singh, S. et al. (2021) Science (New York, N.Y.) 373, eabj5338. PMID: 34516797 | ||||||||
| Note | For research use only. |

Western blot analysis was performed using anti-RPS19 polyclonal antibody at 1μg/ml on various samples.
Lane 1: Mouse liver lysate
Lane 2: Rat liver lysate
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