Anti-Human S100A4 Recombinant Antibody (5C3) (HB727013)

Name: Anti-Human S100A4 Recombinant Antibody (5C3)
Brand: abinScience
SKU: HB727013
Price: 191 USD
Availability: InStock

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Overview

Catalog No.	HB727013
Brand	abinScience
Species reactivity	Monkey, Macaca mulatta (Rhesus macaque)
Applications	FuncS, IHC, Neut, Inhib
Host species	Mouse
Isotype	IgG1, kappa
Clone ID	5C3
Clonality	Monoclonal
Target	Protein S100-A4, Calvasculin, Metastasin, Placental calcium-binding protein, Protein Mts1, S100 calcium-binding protein A4, S100A4, CAPL, MTS1
Endotoxin level	Please contact with the lab for this information.
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P26447, P07091
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background	Protein S100-A4 (S100A4) is a ~11 kDa protein. Calcium-binding protein that plays a role in various cellular processes including motility, angiogenesis, cell differentiation, apoptosis, and autophagy. Increases cell motility and invasiveness by interacting with non-muscle myosin heavy chain (NMMHC) IIA/MYH9. Mechanistically, promotes filament depolymerization and increases the amount of soluble myosin-IIA, resulting in the formation of stable protrusions facilitating chemotaxis. Also modulates the pro-apoptotic function of TP53 by binding to its C-terminal transactivation domain within the nucleus and reducing its protein levels. Within the extracellular space, stimulates cytokine production including granulocyte colony-stimulating factor and CCL24 from T-lymphocytes. 1. Li, ZH. et al. (2006) Cancer research 66, 5173-80. PMID: 16707441 2. Orre, LM. et al. (2013) Oncogene 32, 5531-40. PMID: 23752197 3. Sharapova, TN. et al. (2018) Acta naturae 10, 115-120. PMID: 30713770 4. Dukhanina, EA. et al. (2015) Cell cycle (Georgetown, Tex.) 14, 3635-43. PMID: 26654597
Note	For research use only

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SDS-PAGE for Anti-Human S100A4 Antibody (5C3)

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Datasheet

Anti-Human S100A4 Recombinant Antibody (5C3).pdf

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Anti-Human S100A4 Recombinant Antibody (5C3) (HB727013)

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