Anti-Human S100B Monoclonal Antibody (1A295) (HY256085)

Name: Anti-Human S100B Monoclonal Antibody (1A295)
Brand: abinScience
SKU: HY256085
Price: 194 USD
Availability: InStock

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Overview

Catalog No.	HY256085
Description	Anti-Human S100B Monoclonal Antibody (1A295) [1A295] (HY256085) is a mouse monoclonal antibody detecting S100B in ELISA, IFA. Suitable for Human.
Species reactivity	Human
Applications	ELISA, IFA
Host species	Mouse
Clonality	Monoclonal
Isotype	IgG
Clone ID	1A295
Immunogen	Human S100B Protein.
Target	Protein S100-B, S-100 protein beta chain, S-100 protein subunit beta, S100 calcium-binding protein B, S100B
Endotoxin level	Please contact with the lab for this information.
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P04271
Form	Liquid
Storage buffer	0.01M PBS pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background	Protein S100-B (S100B) is a ~10 kDa protein. Small zinc- and- and calcium-binding protein that is highly expressed in astrocytes and constitutes one of the most abundant soluble proteins in brain. Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Acts as a neurotrophic factor that promotes astrocytosis and axonal proliferation. Involved in innervation of thermogenic adipose tissue by acting as an adipocyte-derived neurotrophic factor that promotes sympathetic innervation of adipose tissue. 1. Ostendorp, T. et al. (2011) Biochimica et biophysica acta 1813, 1083-91. PMID: 20950652 2. Baudier, J. et al. (1984) Biochimica et biophysica acta 790, 164-73. PMID: 6487634 3. Gilquin, B. et al. (2010) Molecular and cellular biology 30, 2724-36. PMID: 20351179 4. Yamaguchi, F. et al. (2012) The Journal of biological chemistry 287, 13787-98. PMID: 22399290
Note	For research use only.

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SDS-PAGE

SDS-PAGE for Anti-Human S100B Monoclonal Antibody (1A295)

References

Datasheet

Anti-Human S100B Monoclonal Antibody (1A295).pdf

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Formula

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Anti-Human S100B Monoclonal Antibody (1A295) (HY256085)

Overview

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References

Datasheet

SDS