Anti-Human SCARB1/SR-BI/CLA-1/SRB1 Polyclonal Antibody (HP511014)

Name: Anti-Human SCARB1/SR-BI/CLA-1/SRB1 Polyclonal Antibody
Brand: abinScience
SKU: HP511014
Price: 168 USD
Availability: InStock

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Overview

Catalog No.

HP511014

Description

Anti-Human SCARB1/SR-BI/CLA-1/SRB1 Polyclonal Antibody (HP511014) is a rabbit polyclonal antibody detecting SR-BI in ELISA, IHC, WB. Suitable for Human, Pig, Dog, and Cat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human SCARB1/SR-BI/CLA-1/SRB1 (Ile61-Gly424).

Target

Scavenger receptor class B member 1, SRB1, CD36 and LIMPII analogous 1, CLA-1, CD36 antigen-like 1, Collagen type I receptor, thrombospondin receptor-like 1, SR-BI, CD36, SCARB1, CD36L1, CLA1

Endotoxin level

Please contact with the lab for this information.

Purification

Purified by antigen affinity column.

Accession

Q8WTV0, Q8SQC1

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Scavenger receptor class B member 1 (SCARB1/SR-BI) is a ~60 kDa protein. Receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells. Receptor for HDL, mediating selective uptake of cholesteryl ether and HDL-dependent cholesterol efflux. Also facilitates the flux of free and esterified cholesterol between the cell surface and apoB-containing lipoproteins and modified lipoproteins, although less efficiently than HDL. May be involved in the phagocytosis of apoptotic cells, via its phosphatidylserine binding activity.

1. Kawasaki, Y. et al. (2002) The Journal of biological chemistry 277, 27559-66. PMID: 12016218

2. Tai, ES. et al. (2003) Clinical genetics 63, 53-8. PMID: 12519372

3. Vergeer, M. et al. (2011) The New England journal of medicine 364, 136-45. PMID: 21226579

4. Zanoni, P. et al. (2016) Science (New York, N.Y.) 351, 1166-71. PMID: 26965621

Note

For research use only.

Images

References

Datasheet

Anti-Human SCARB1/SR-BI/CLA-1/SRB1 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human SCARB1/SR-BI/CLA-1/SRB1 Polyclonal Antibody (HP511014)

Overview

Images

References

Datasheet

SDS

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