Anti-Human SDHA Polyclonal Antibody (HB711014)

Name: Anti-Human SDHA Polyclonal Antibody
Brand: abinScience
SKU: HB711014
Price: 168 USD
Availability: InStock

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SDS

Overview

Catalog No.

HB711014

Description

Anti-Human SDHA Polyclonal Antibody (HB711014) is a rabbit polyclonal antibody detecting SDHA in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bovine, and Danio rerio.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Species reactivity

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human SDHA (Ser44-Tyr664).

Target

SDH2, Flavoprotein subunit of complex II, Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial, SDHA, SDHF, Fp

Purification

Purified by antigen affinity column.

Accession

P31040

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial (SDHA) is a ~72 kDa protein. Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). SDH also oxidizes malate to the non-canonical enol form of oxaloacetate, enol-oxaloacetate. Enol-oxaloacetate, which is a potent inhibitor of the succinate dehydrogenase activity, is further isomerized into keto-oxaloacetate. Can act as a tumor suppressor.

1. Parfait, B. et al. (2000) Human genetics 106, 236-43. PMID: 10746566

2. Renkema, GH. et al. (2015) European journal of human genetics : EJHG 23, 202-9. PMID: 24781757

3. Burnichon, N. et al. (2010) Human molecular genetics 19, 3011-20. PMID: 20484225

Note

For research use only.

Images

References

Datasheet

Anti-Human SDHA Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human SDHA Polyclonal Antibody (HB711014)

Overview

Images

References

Datasheet

SDS

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