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Anti-Human SGPP2 Polyclonal Antibody (HA355014)

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Overview
Catalog No.HA355014
Description
Anti-Human SGPP2 Polyclonal Antibody (HA355014) is a rabbit polyclonal antibody detecting SGPP2 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Species reactivityHuman, Mouse
ApplicationsELISA, IHC, WB
Host speciesRabbit
ClonalityPolyclonal
IsotypeIgG
Immunogen E. coli - derived recombinant Human SGPP2 (Ala2-Tyr87).
Target Sphingosine-1-phosphate phosphatase 2, SPPase2, Spp2, hSPP2, 3.1.3.-, Sphingosine-1-phosphatase 2, SGPP2
Purification Purified by antigen affinity column.
Accession Q8IWX5
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Sphingosine-1-phosphate phosphatase 2 (SGPP2) is a ~44 kDa protein. Has specific phosphohydrolase activity towards sphingoid base 1-phosphates. Has high phosphohydrolase activity against dihydrosphingosine-1-phosphate and sphingosine-1-phosphate (S1P) in vitro. Sphingosine-1-phosphate phosphatase activity is needed for efficient recycling of sphingosine into the sphingolipid synthesis pathway. May play a role in attenuating intracellular sphingosine 1-phosphate (S1P) signaling. May play a role in pro-inflammatory signaling.

1. Ogawa, C. et al. (2003) The Journal of biological chemistry 278, 1268-72. PMID: 12411432
2. Mechtcheriakova, D. et al. (2007) Cellular signalling 19, 748-60. PMID: 17113265
Note For research use only.
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Datasheet
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-Human SGPP2 Polyclonal Antibody

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