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Anti-Human SGSM3 Polyclonal Antibody (HD154014)

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Overview
Catalog No.HD154014
Description
Anti-Human SGSM3 Polyclonal Antibody (HD154014) is a rabbit polyclonal antibody detecting SGSM3. Suitable for Rat, Mouse, and Human.
Highlights
  • Multi-Species — Cross-reactive for translational research.
Species reactivityHuman, Mouse, Rat
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human SGSM3 (Met1-Gly382).
Target MAP, Merlin-associated protein, RABGAPLP, RUN and TBC1 domain-containing protein 3, RUTBC3, Rab-GTPase-activating protein-like protein, RabGAPLP, SGSM3, Small G protein signaling modulator 3
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession Q96HU1
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

Small G protein signaling modulator 3 (SGSM3) is a ~85 kDa protein. GTPase-activating protein (GAP) specific for Rab5 small GTPase for which it accelerates the intrinsic GTP hydrolysis rate, thereby controlling trafficking through the early endocytic pathway. May play a cooperative role in NF2-mediated growth suppression of cells.

1. Haas, AK. et al. (2005) Nature cell biology 7, 887-93. PMID: 16086013
2. Fuchs, E. et al. (2007) The Journal of cell biology 177, 1133-43. PMID: 17562788
Note For research use only
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Formula
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