

| Catalog No. | HD154014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human SGSM3 Polyclonal Antibody (HD154014) is a rabbit polyclonal antibody detecting SGSM3. Suitable for Rat, Mouse, and Human.
Highlights
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| Species reactivity | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human SGSM3 (Met1-Gly382). | ||||||||
| Target | MAP, Merlin-associated protein, RABGAPLP, RUN and TBC1 domain-containing protein 3, RUTBC3, Rab-GTPase-activating protein-like protein, RabGAPLP, SGSM3, Small G protein signaling modulator 3 | ||||||||
| Endotoxin level | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q96HU1 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Background | Small G protein signaling modulator 3 (SGSM3) is a ~85 kDa protein. GTPase-activating protein (GAP) specific for Rab5 small GTPase for which it accelerates the intrinsic GTP hydrolysis rate, thereby controlling trafficking through the early endocytic pathway. May play a cooperative role in NF2-mediated growth suppression of cells. 1. Haas, AK. et al. (2005) Nature cell biology 7, 887-93. PMID: 16086013 2. Fuchs, E. et al. (2007) The Journal of cell biology 177, 1133-43. PMID: 17562788 | ||||||||
| Note | For research use only |
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