Anti-Human SLC25A12 Polyclonal Antibody (HF639014)

Name: Anti-Human SLC25A12 Polyclonal Antibody
Brand: abinScience
SKU: HF639014
Price: 96 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HF639014

Description

Anti-Human SLC25A12 Polyclonal Antibody (HF639014) is a rabbit polyclonal antibody detecting SLC25A12 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human SLC25A12 (Gly11-Gln311).

Target

Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial, Araceli hiperlarga, Aralar, Aralar1, Mitochondrial aspartate glutamate carrier 1, Solute carrier family 25 member 12, SLC25A12, AGC1, ARALAR1

Purification

Purified by antigen affinity column.

Accession

O75746

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial is a ~74 kDa protein. Mitochondrial electrogenic aspartate/glutamate antiporter that favors efflux of aspartate and entry of glutamate and proton within the mitochondria as part of the malate-aspartate shuttle. Also mediates the uptake of L-cysteinesulfinate (3-sulfino-L-alanine) by mitochondria in exchange of L-glutamate and proton. Can also exchange L-cysteinesulfinate with aspartate in their anionic form without any proton translocation. Lacks transport activity towards L-glutamine or gamma-aminobutyric acid (GABA).

1. Palmieri, L. et al. (2001) The EMBO journal 20, 5060-9. PMID: 11566871

2. Wibom, R. et al. (2009) The New England journal of medicine 361, 489-95. PMID: 19641205

3. Falk, MJ. et al. (2014) JIMD reports 14, 77-85. PMID: 24515575

4. Porcelli, V. et al. (2024) Biochimica et biophysica acta. Bioenergetics 1865, 149487. PMID: 38945283

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-SLC25A12 polyclonal antibody at SLC25A12 on various samples.
Lane 1: Jurkat cell lysate
Lane 2: A431 cell lysate
Lane 3: Mouse brain lysate
Lane 4: Mouse skeletal muscle lysate
Lane 5: Rat brain lysate
Lane 6: Rat skeletal muscle lysate

References

Datasheet

Anti-Human SLC25A12 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human SLC25A12 Polyclonal Antibody (HF639014)

Overview

Images

References

Datasheet

SDS

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