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Anti-Human SLC26A8 Polyclonal Antibody (HV071014)

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Overview
Catalog No.HV071014
Species reactivityHuman
ApplicationsELISA, IHC, WB
Host speciesRabbit
ClonalityPolyclonal
IsotypeIgG
Immunogen E. coli - derived recombinant Human SLC26A8 (Thr664-Val970).
Target Solute carrier family 26 member 8, SLC26A8, Testis anion transporter 1, TAT1, Anion exchange transporter
Purification Purified by antigen affinity column.
Accession Q96RN1
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Testis anion transporter 1 (SLC26A8) is a ~109 kDa protein. Antiporter that mediates the exchange of sulfate and oxalate against chloride ions across a membrane. Stimulates anion transport activity of CFTR. May cooperate with CFTR in the regulation of chloride and bicarbonate ions fluxes required for activation of the ADCY10/PKA pathway during sperm motility and sperm capacitation. May play a role in sperm tail differentiation and motility and hence male fertility.

1. Toure, A. et al. (2001) The Journal of biological chemistry 276, 20309-15. PMID: 11278976
2. Lohi, H. et al. (2002) The Journal of biological chemistry 277, 14246-54. PMID: 11834742
3. Rode, B. et al. (2012) Human molecular genetics 21, 1287-98. PMID: 22121115
4. Dirami, T. et al. (2013) American journal of human genetics 92, 760-6. PMID: 23582645
Note For research use only.
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-Human SLC26A8 Polyclonal Antibody

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