Anti-Human SLC27A2 Polyclonal Antibody (HT300014)

Name: Anti-Human SLC27A2 Polyclonal Antibody
Brand: abinScience
SKU: HT300014
Price: 168 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HT300014

Description

Anti-Human SLC27A2 Polyclonal Antibody (HT300014) is a rabbit polyclonal antibody detecting SLC27A2 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Immunogen

E. coli - derived recombinant Human SLC27A2 (Gly283-Leu620).

Target

Long-chain fatty acid transport protein 2, Arachidonate--CoA ligase, 6.2.1.15, Fatty acid transport protein 2, FATP-2, Fatty-acid-coenzyme A ligase, very long-chain 1, Long-chain-fatty-acid--CoA ligase, 6.2.1.3, Phytanate--CoA ligase, 6.2.1.24, Solute carrier family 27 member 2, THCA-CoA ligase, 6.2.1.7, Very long-chain acyl-CoA synthetase, VLACS, VLCS, 6.2.1.-, Very long-chain-fatty-acid-CoA ligase, SLC27A2, ACSVL1, FACVL1, FATP2, VLACS

Purification

Purified by antigen affinity column.

Accession

O14975

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Long-chain fatty acid transport protein 2 (SLC27A2) is a ~70 kDa protein. Mediates the import of long-chain fatty acids (LCFA) into the cell by facilitating their transport across cell membranes, playing an important role in hepatic fatty acid uptake. Also functions as an acyl-CoA ligase catalyzing the ATP-dependent formation of fatty acyl-CoA using LCFA and very-long-chain fatty acids (VLCFA) as substrates, which prevents fatty acid efflux from cells and might drive more fatty acid uptake. Plays a pivotal role in regulating available LCFA substrates from exogenous sources in tissues undergoing high levels of beta-oxidation or triglyceride synthesis. Can also activate branched-chain fatty acids such as phytanic acid and pristanic acid. May contribute to the synthesis of sphingosine-1-phosphate.

1. Steinberg, SJ. et al. (1999) Biochemical and biophysical research communications 257, 615-21. PMID: 10198260

2. Steinberg, SJ. et al. (2000) The Journal of biological chemistry 275, 15605-8. PMID: 10749848

3. Mihalik, SJ. et al. (2002) The Journal of biological chemistry 277, 24771-9. PMID: 11980911

4. Falcon, A. et al. (2010) American journal of physiology. Endocrinology and metabolism 299, E384-93. PMID: 20530735

5. Krammer, J. et al. (2011) International journal of medical sciences 8, 599-614. PMID: 22022213

6. Ohkuni, A. et al. (2013) Biochemical and biophysical research communications 442, 195-201. PMID: 24269233

Note

For research use only.

Images

References

Datasheet

Anti-Human SLC27A2 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human SLC27A2 Polyclonal Antibody (HT300014)

Overview

Images

References

Datasheet

SDS