

| Catalog No. | HP141014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Species reactivity | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Clonality | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogen | E. coli - derived recombinant Human SLC2A9 (Pro253-Gln316). | ||||||||
| Target | GLUT-9, SLC2A9, Glucose transporter type 9, Solute carrier family 2, facilitated glucose transporter member 9, Urate transporter, GLUT9 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q9NRM0 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Solute carrier family 2, facilitated glucose transporter member 9 (SLC2A9) is a ~58 kDa protein. High-capacity urate transporter, which may play a role in the urate reabsorption by proximal tubules. May have a residual high-affinity, low-capacity glucose and fructose transporter activity. Transports urate at rates 45- to 60-fold faster than glucose. Does not transport galactose. May mediate small uptake of adenine but not of other nucleobases. 1. Vitart, V. et al. (2008) Nature genetics 40, 437-42. PMID: 18327257 2. Anzai, N. et al. (2008) The Journal of biological chemistry 283, 26834-8. PMID: 18701466 3. Witkowska, K. et al. (2012) American journal of physiology. Renal physiology 303, F527-39. PMID: 22647630 4. Ebert, K. et al. (2017) The Journal of membrane biology 250, 171-182. PMID: 28083649 5. Toyoda, Y. et al. (2023) Pflugers Archiv : European journal of physiology 475, 489-504. PMID: 36749388 6. Caulfield, MJ. et al. (2008) PLoS medicine 5, e197. PMID: 18842065 | ||||||||
| Note | For research use only. |
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