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Anti-Human SLC30A6 Polyclonal Antibody (HP576014)

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Overview
Catalog No.HP576014
Species reactivityHuman
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human SLC30A6 (Ser247-Asp334).
Target ZnT-6, Solute carrier family 30 member 6, Zinc transporter 6, ZNT6, SLC30A6
Purification Purified by antigen affinity column.
Accession Q6NXT4
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Zinc transporter 6 (SLC30A6) is a ~51 kDa protein. Has probably no intrinsic transporter activity but together with SLC30A5 forms a functional zinc ion:proton antiporter heterodimer, mediating zinc entry into the lumen of organelles along the secretory pathway. As part of that zinc ion:proton antiporter, contributes to zinc ion homeostasis within the early secretory pathway and regulates the activation and folding of enzymes like alkaline phosphatases and enzymes involved in phosphatidylinositol glycan anchor biosynthesis.

1. Suzuki, T. et al. (2005) The Journal of biological chemistry 280, 30956-62. PMID: 15994300
2. Ohana, E. et al. (2009) The Journal of biological chemistry 284, 17677-86. PMID: 19366695
3. Fukunaka, A. et al. (2009) The Journal of biological chemistry 284, 30798-806. PMID: 19759014
4. Wagatsuma, T. et al. (2022) The Journal of biological chemistry 298, 102011. PMID: 35525268
Note For research use only.
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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