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Anti-Human SLC35B1 Recombinant Antibody (SAA2353) (HC089013)

Anti-Human SLC35B1 Recombinant Antibody (SAA2353)
Anti-Human SLC35B1 Recombinant Antibody (SAA2353)
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Overview
Catalog No.HC089013
Species reactivityHuman
ApplicationsELISA
Host speciesMouse
IsotypeIgG
Clone IDSAA2353
Clonality Monoclonal
Target Solute carrier family 35 member B1, ATP/ADP exchanger ER, AXER, Endoplasmic reticulum ATP/ADP translocase, UDP-galactose transporter-related protein 1, UGTrel1, SLC35B1, UGTREL1
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession P78383
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:2000-1:20000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Solute carrier family 35 member B1 (SLC35B1) is a ~35 kDa protein. ATP:ADP antiporter that catalyzes the exchange of ATP and ADP across the endoplasmic reticulum (ER) membrane. Imports ATP from the cytosol to the ER lumen and exports ADP in the opposite direction. Regulates ER energy metabolism and protein biogenesis. Appears to be part of a calcium-dependent ER to cytosol low energy response axis, where calcium efflux from ER to the cytosol triggers ATP import into the ER lumen to maintain sufficient ATP supply. Provides ATP to ER chaperone HSPA5 that drives protein folding and trafficking in the ER.

1. Klein, MC. et al. (2018) Nature communications 9, 3489. PMID: 30154480
2. Schwarzbaum, PJ. et al. (2022) The Journal of biological chemistry 298, 101537. PMID: 35041824
3. Gulati, A. et al. (2025) Nature 643, 855-864. PMID: 40399679
Note For research use only
Images
  • Anti-Human SLC35B1 Recombinant Antibody (SAA2353)

    SDS-PAGE

    SDS-PAGE for Anti-Human SLC35B1 Antibody (SAA2353)

References
Formula
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