Anti-Human SLPI Recombinant Antibody (SAA1833) (HY298013)

Name: Anti-Human SLPI Recombinant Antibody (SAA1833)
Brand: abinScience
SKU: HY298013
Price: 196 USD
Availability: InStock

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50ug
100ug
1mg

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HY298013

Species reactivity

Human

Applications

ELISA, WB

Host species

Mouse

Isotype

IgG2a, kappa

Clone ID

SAA1833

Clonality

Monoclonal

Target

WFDC4, ALP, Antileukoproteinase, WAP four-disulfide core domain protein 4, SLPI, BLPI, Secretory leukocyte protease inhibitor, WAP4, Mucus proteinase inhibitor, HUSI-1, Seminal proteinase inhibitor, MPI, Protease inhibitor WAP4

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P03973

RRID

Anti-Human SLPI Antibody (SAA1833) (abinScience Cat# HY298013, RRID:AB_3727596)
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Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Antileukoproteinase (SLPI) is a ~14 kDa protein. Acid-stable proteinase inhibitor with strong affinities for trypsin, chymotrypsin, elastase, and cathepsin G. Modulates the inflammatory and immune responses after bacterial infection, and after infection by the intracellular parasite L.major. Down-regulates responses to bacterial lipopolysaccharide (LPS). Plays a role in regulating the activation of NF-kappa-B and inflammatory responses. Has antimicrobial activity against mycobacteria, but not against salmonella.

1. Mulligan, MS. et al. (2000) The American journal of pathology 156, 1033-9. PMID: 10702419

2. Sallenave, JM. et al. (1991) Biological chemistry Hoppe-Seyler 372, 13-21. PMID: 2039600

3. Eisenberg, SP. et al. (1990) The Journal of biological chemistry 265, 7976-81. PMID: 2110563

4. Fukushima, K. et al. (2013) Journal of synchrotron radiation 20, 943-7. PMID: 24121345

5. Thompson, RC. et al. (1986) Proceedings of the National Academy of Sciences of the United States of America 83, 6692-6. PMID: 3462719

6. Heinzel, R. et al. (1986) European journal of biochemistry 160, 61-7. PMID: 3533531

7. Klimenkova, O. et al. (2014) Blood 123, 1239-49. PMID: 24352879

Note

For research use only.

Isotype Control

Mouse IgG2a, kappa Recombinant Isotype Control Antibody (MOPC-173) (MF533507)

Images

SDS-PAGE

SDS-PAGE for Anti-Human SLPI Antibody (SAA1833)
Bioactivity

Detects recombinant SLPI (Catalog No: HY298022) in indirect ELISA.
Western blot

Lane 1: recombinant human SLPI (Catalog No: HY298022)
Lane 2: 1*loading buffer