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Anti-Human SLURP2 Polyclonal Antibody (HC987014)

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Overview
Catalog No.HC987014
Description
Anti-Human SLURP2 Polyclonal Antibody (HC987014) is a rabbit polyclonal antibody detecting SLURP2. Suitable for Human.
Species reactivityHuman
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human SLURP2 (Ile23-Asp97).
Target SLURP-2, SLURP2, Secreted LY6/PLAUR domain-containing protein 2, Secreted Ly-6/uPAR domain-containing protein 2, Secreted Ly-6/uPAR-related protein 2
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession P0DP57
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

Secreted Ly-6/uPAR domain-containing protein 2 (SLURP2) is a ~10 kDa protein. Binds and may modulate the functional properties of nicotinic and muscarinic acetylcholine receptors. May regulate keratinocytes proliferation, differentiation and apoptosis. In vitro moderately inhibits ACh-evoked currents of alpha-3:beta-2-containing nAChRs and strongly these of alpha-4:beta-2-containing nAChRs, modulates alpha-7-containing nAChRs, and inhibits nicotine-induced signaling probably implicating alpha-3:beta-4-containing nAChRs. Proposed to act on alpha-3:beta-2 and alpha-7 nAChRs in an orthosteric, and on mAChRs, such as CHRM1 and CHRM3, in an allosteric manner.

Note For research use only
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Formula
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Anti-Human SLURP2 Polyclonal Antibody

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