

| Catalog No. | HV964014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human SMOX Polyclonal Antibody (HV964014) is a rabbit polyclonal antibody detecting SMOX in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Species reactivity | Human, Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human SMOX (Met1-Gln165). | ||||||||
| Target | Spermine oxidase, PAO-1, PAOh1, C20orf16, SMOX, SMO, Polyamine oxidase 1 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q9NWM0 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Spermine oxidase (SMOX) is a ~61 kDa protein. Flavoenzyme which catalyzes the oxidation of spermine to spermidine. Can also use N(1)-acetylspermine and spermidine as substrates, with different affinity depending on the isoform (isozyme) and on the experimental conditions. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs. May contribute to beta-alanine production via aldehyde dehydrogenase conversion of 3-amino-propanal. | ||||||||
| Note | For research use only. |

Western blot analysis was performed using anti-SMOX polyclonal antibody at 1ug/mL on various samples.
Lane 1: A549 cell lysate
Lane 2: MCF-7 cell lysate
Lane 3: PC-3 cell lysate
Lane 4: 293T cell lysate
Lane 5: C2C12 cell lysate
Lane 6: Mouse testis lysate
Lane 7: Mouse liver lysate
Lane 8: Mouse pancears lysate
Lane 9: Rat testis lysate
Lane 10: Rat liver lysate
Lane11: Rat pancears lysate
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