

| Catalog No. | HY241014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Species reactivity | Human, Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Clonality | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogen | E. coli - derived recombinant Human SNRPA1 (Met1-Arg176). | ||||||||
| Target | U2 small nuclear ribonucleoprotein A', SNRPA1, U2 snRNP A' | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | P09661 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | U2 small nuclear ribonucleoprotein A' (SNRPA1) is a ~28 kDa protein. Involved in pre-mRNA splicing as component of the spliceosome. Associated with sn-RNP U2, where it contributes to the binding of stem loop IV of U2 snRNA. 1. Jurica, MS. et al. (2002) RNA (New York, N.Y.) 8, 426-39. PMID: 11991638 2. Wu, H. et al. (2016) Proceedings of the National Academy of Sciences of the United States of America 113, 4134-9. PMID: 27035939 3. Bertram, K. et al. (2017) Nature 542, 318-323. PMID: 28076346 4. Zhang, X. et al. (2017) Cell 169, 918-929.e14. PMID: 28502770 5. Bertram, K. et al. (2017) Cell 170, 701-713.e11. PMID: 28781166 6. Zhang, Z. et al. (2020) Nature 583, 310-313. PMID: 32494006 7. Price, SR. et al. (1998) Nature 394, 645-50. PMID: 9716128 | ||||||||
| Note | For research use only. |
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