Anti-Human SNX2 Polyclonal Antibody (HT141014)

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References
Datasheet
SDS

Overview

Catalog No.

HT141014

Description

Anti-Human SNX2 Polyclonal Antibody (HT141014) is a rabbit polyclonal antibody detecting SNX2 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human SNX2 (Asp125-Ser277).

Target

Sorting nexin-2, Transformation-related gene 9 protein, TRG-9, SNX2, TRG9

Purification

Purified by antigen affinity column.

Accession

O60749

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Sorting nexin-2 (SNX2) is a ~58 kDa protein. Involved in several stages of intracellular trafficking. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)) or phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Acts in part as component of the retromer membrane-deforming SNX-BAR subcomplex. The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling. The SNX-BAR subcomplex functions to deform the donor membrane into a tubular profile called endosome-to-TGN transport carrier (ETC) (Probable).

1. Carlton, JG. et al. (2005) Journal of cell science 118, 4527-39. PMID: 16179610

2. Rojas, R. et al. (2007) Molecular and cellular biology 27, 1112-24. PMID: 17101778

3. van Weering, JR. et al. (2012) The EMBO journal 31, 4466-80. PMID: 23085988

4. Lieu, ZZ. et al. (2010) European journal of cell biology 89, 379-93. PMID: 20138391

5. Prosser, DC. et al. (2010) Traffic (Copenhagen, Denmark) 11, 1347-62. PMID: 20604901

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-Human SNX2 polyclonal antibody at 1ug/mL on recombinant Human SNX2 (Catalog No. HT141012).

References

Datasheet

Anti-Human SNX2 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human SNX2 Polyclonal Antibody (HT141014)

Overview

Images

References

Datasheet

SDS

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