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Anti-Human SORBS2 Polyclonal Antibody (HF679014)

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Overview
Catalog No.HF679014
Species reactivityHuman, Mouse, Rat
ApplicationsELISA, IHC, WB
Host speciesRabbit
ClonalityPolyclonal
IsotypeIgG
Immunogen E. coli - derived recombinant Human SORBS2 (Lys865-Thr1001).
Target Sorbin and SH3 domain-containing protein 2, ArgBP2, Arg/Abl-interacting protein 2, Sorbin, KIAA0777, ARGBP2, SORBS2, Arg-binding protein 2
Purification Purified by antigen affinity column.
Accession O94875
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Sorbin and SH3 domain-containing protein 2 (SORBS2) is a ~124 kDa protein. Adapter protein that plays a role in the assembling of signaling complexes, being a link between ABL kinases and actin cytoskeleton. Can form complex with ABL1 and CBL, thus promoting ubiquitination and degradation of ABL1. May play a role in the regulation of pancreatic cell adhesion, possibly by acting on WASF1 phosphorylation, enhancing phosphorylation by ABL1, as well as dephosphorylation by PTPN12. Isoform 6 increases water and sodium absorption in the intestine and gall-bladder.

1. Taieb, D. et al. (2008) Cancer research 68, 4588-96. PMID: 18559503
Note For research use only.
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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Anti-Human SORBS2 Polyclonal Antibody

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