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Anti-Human SOS2 Polyclonal Antibody (HD170014)

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Overview
Catalog No.HD170014
Description
Anti-Human SOS2 Polyclonal Antibody (HD170014) is a rabbit polyclonal antibody detecting SOS2. Suitable for Human and Mouse.
Highlights
  • Multi-Species — Cross-reactive for translational research.
Species reactivityHuman, Mouse
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human SOS2 (Met1-Asn561).
Target SOS-2, SOS2, Son of sevenless homolog 2
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession Q07890
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

Son of sevenless homolog 2 (SOS2) is a ~152 kDa protein. Acts as guanine nucleotide exchange factor (GEF) for RAS proteins. Catalyzes the GDP-to-GTP exchange, resulting in an increase of the active GTP-bound form of HRAS. Acts as a key modulator of PI3K-AKT signaling.

1. Liu, AM. et al. (2010) Cellular signalling 22, 1448-58. PMID: 20639119
Note For research use only
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
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Concentration
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Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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