Anti-Human SOX10 Polyclonal Antibody (HX928024)

Name: Anti-Human SOX10 Polyclonal Antibody
Brand: abinScience
SKU: HX928024
Price: 168 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HX928024

Description

Anti-Human SOX10 Polyclonal Antibody (HX928024) is a rabbit polyclonal antibody detecting Transcription factor SOX-10; SOX10. Suitable for Rat, Human, and Mouse.

Highlights

●Multi-Species — Cross-reactive for translational research.

Species reactivity

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human SOX10 (Lys67-Asp170).

Target

Transcription factor SOX-10; SOX10

Endotoxin level

Please contact with the lab for this information.

Purification

Purified by antigen affinity column.

Accession

P56693

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Background

Transcription factor SOX-10 (SOX10) is a ~49 kDa protein. Transcription factor that plays a central role in developing and mature glia. Specifically activates expression of myelin genes, during oligodendrocyte (OL) maturation, such as DUSP15 and MYRF, thereby playing a central role in oligodendrocyte maturation and CNS myelination. Once induced, MYRF cooperates with SOX10 to implement the myelination program. Transcriptional activator of MITF, acting synergistically with PAX3. Transcriptional activator of MBP, via binding to the gene promoter.

1. Zhang, H. et al. (2012) Human genetics 131, 491-503. PMID: 21965087

Note

For research use only

Images

Western blot

Lane 1: MDA-MB-453 cell lysate

References

Datasheet

Anti-Human SOX10 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human SOX10 Polyclonal Antibody (HX928024)

Overview

Images

References

Datasheet

SDS

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