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Anti-Human SOX11 Polyclonal Antibody (HD615014)

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Overview
Catalog No.HD615014
Description
Anti-Human SOX11 Polyclonal Antibody (HD615014) is a rabbit polyclonal antibody detecting SOX11. Suitable for Rat, Mouse, and Human.
Highlights
  • ●Multi-Species — Cross-reactive for translational research.
Species reactivityHuman, Mouse, Rat
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human SOX11 (Asn54-Tyr113).
Target SOX11, Transcription factor SOX-11
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession P35716
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

Transcription factor SOX-11 (SOX11) is a ~46 kDa protein. Transcription factor that acts as a transcriptional activator. Binds cooperatively with POU3F2/BRN2 or POU3F1/OCT6 to gene promoters, which enhances transcriptional activation. Acts as a transcriptional activator of TEAD2 by binding to its gene promoter and first intron. Plays a redundant role with SOX4 and SOX12 in cell survival of developing tissues such as the neural tube, branchial arches and somites, thereby contributing to organogenesis.

1. Tsurusaki, Y. et al. (2014) Nature communications 5, 4011. PMID: 24886874
2. Hempel, A. et al. (2016) Journal of medical genetics 53, 152-62. PMID: 26543203
Note For research use only
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Datasheet
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
C₁ × V₁ = C₂ × V₂
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Stock Solution
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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Anti-Human SOX11 Polyclonal Antibody

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