Anti-Human SPNS2 Recombinant Antibody (SAA1862) (HA888013)

Name: Anti-Human SPNS2 Recombinant Antibody (SAA1862)
Brand: abinScience
SKU: HA888013
Price: 196 USD
Availability: InStock

Datasheet Share product Copy info

Price(USD):

Spec:

50ug
100ug
1mg

Number:

Get quote

Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HA888013

Species reactivity

Human

Applications

ELISA

Host species

Mouse

Isotype

IgG2a, kappa

Clone ID

SAA1862

Clonality

Monoclonal

Target

Protein spinster homolog 2, SPNS2

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q8IVW8

RRID

Anti-Human SPNS2 Antibody (SAA1862) (abinScience Cat# HA888013, RRID:AB_3727625)
_x005F_x005F_x000D_

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Sphingosine-1-phosphate transporter SPNS2 is a ~58 kDa protein. Lipid transporter that specifically mediates export of sphingosine-1-phosphate (sphing-4-enine 1-phosphate, S1P) and sphinganine-1-phosphate in the lymph, thereby playing a role in lymphocyte trafficking. S1P is a bioactive signaling molecule that regulates many physiological processes important for the development and for the immune system. Regulates levels of S1P and the S1P gradient that exists between the high circulating concentrations of S1P and low tissue levels that control lymphocyte trafficking. Required for the egress of T-cells from lymph nodes during an immune response by mediating S1P secretion, which generates a gradient that enables activated T-cells to access lymph. Also required for the egress of immature B-cells from the bone marrow.

1. Kawahara, A. et al. (2009) Science (New York, N.Y.) 323, 524-7. PMID: 19074308

2. Hisano, Y. et al. (2011) The Journal of biological chemistry 286, 1758-66. PMID: 21084291

3. Nagahashi, M. et al. (2013) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 27, 1001-11. PMID: 23180825

4. Ingham, NJ. et al. (2019) PLoS biology 17, e3000194. PMID: 30973865

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human SPNS2 Antibody (SAA1862)

References

Datasheet

Anti-Human SPNS2 Recombinant Antibody (SAA1862).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human SPNS2 Recombinant Antibody (SAA1862) (HA888013)

Overview

Images

References

Datasheet

SDS

Quick access

Contact Us