Anti-Human SRPRA Polyclonal Antibody (HY369014)

Name: Anti-Human SRPRA Polyclonal Antibody
Brand: abinScience
SKU: HY369014
Price: 96 USD
Availability: InStock

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Overview
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Datasheet
SDS

Overview

Catalog No.

HY369014

Description

Anti-Human SRPRA Polyclonal Antibody (HY369014) is a rabbit polyclonal antibody detecting SRPRA in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Human, Mouse

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human SRPRA (Arg335-Ala638).

Target

Signal recognition particle receptor subunit alpha, SR-alpha, Docking protein alpha, DP-alpha, SRPRA, SRPR

Purification

Purified by antigen affinity column.

Accession

P08240

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Signal recognition particle receptor subunit alpha (SRPRA) is a ~69 kDa protein. Component of the signal recognition particle (SRP) complex receptor (SR). Ensures, in conjunction with the SRP complex, the correct targeting of the nascent secretory proteins to the endoplasmic reticulum membrane system. Forms a guanosine 5'-triphosphate (GTP)-dependent complex with the SRP subunit SRP54. SRP receptor compaction and GTPase rearrangement drive SRP-mediated cotranslational protein translocation into the ER.

1. Schlenker, O. et al. (2006) The Journal of biological chemistry 281, 8898-906. PMID: 16439358

2. Halic, M. et al. (2006) Science (New York, N.Y.) 312, 745-7. PMID: 16675701

3. Lee, JH. et al. (2021) Science advances 7. PMID: 34020957

Note

For research use only.

Images

References

Datasheet

Anti-Human SRPRA Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human SRPRA Polyclonal Antibody (HY369014)

Overview

Images

References

Datasheet

SDS

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