

| Catalog No. | HP422013 | ||||
|---|---|---|---|---|---|
| Species reactivity | Human | ||||
| Applications | ELISA, IF, IP | ||||
| Host species | Mouse | ||||
| Clonality | Monoclonal | ||||
| Isotype | IgG2a | ||||
| Clone ID | SAA0231 | ||||
| Target | SRRT, Arsenite-resistance protein 2, Serrate RNA effector molecule homolog, ARS2, ASR2 | ||||
| Endotoxin level | Please contact with the lab for this information. | ||||
| Purity | >95% as determined by SDS-PAGE. | ||||
| Purification | Protein A/G purified from cell culture supernatant. | ||||
| Accession | Q9BXP5 | ||||
| Form | Liquid | ||||
| Storage buffer | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| Background | Serrate RNA effector molecule homolog (SRRT) is a ~100 kDa protein. Acts as a mediator between the cap-binding complex (CBC) and the primary microRNAs (miRNAs) processing machinery during cell proliferation. Contributes to the stability and delivery of capped primary miRNA transcripts to the primary miRNA processing complex containing DGCR8 and DROSHA, thereby playing a role in RNA-mediated gene silencing (RNAi) by miRNAs. Binds capped RNAs (m7GpppG-capped RNA); however interaction is probably mediated via its interaction with NCBP1/CBP80 component of the CBC complex. Involved in cell cycle progression at S phase. Does not directly confer arsenite resistance but rather modulates arsenic sensitivity. | ||||
| Note | For research use only. |

SDS-PAGE for Anti-Human SRRT IP Antibody (SAA0231)
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