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Anti-Human SRRT IP Recombinant Antibody (SAA0231) (HP422013)

Anti-Human SRRT IP Recombinant Antibody (SAA0231)
Anti-Human SRRT IP Recombinant Antibody (SAA0231)
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Overview
Catalog No.HP422013
Species reactivityHuman
ApplicationsELISA, IF, IP
Host speciesMouse
ClonalityMonoclonal
IsotypeIgG2a
Clone IDSAA0231
Target SRRT, Arsenite-resistance protein 2, Serrate RNA effector molecule homolog, ARS2, ASR2
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession Q9BXP5
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:2000-1:20000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background

Serrate RNA effector molecule homolog (SRRT) is a ~100 kDa protein. Acts as a mediator between the cap-binding complex (CBC) and the primary microRNAs (miRNAs) processing machinery during cell proliferation. Contributes to the stability and delivery of capped primary miRNA transcripts to the primary miRNA processing complex containing DGCR8 and DROSHA, thereby playing a role in RNA-mediated gene silencing (RNAi) by miRNAs. Binds capped RNAs (m7GpppG-capped RNA); however interaction is probably mediated via its interaction with NCBP1/CBP80 component of the CBC complex. Involved in cell cycle progression at S phase. Does not directly confer arsenite resistance but rather modulates arsenic sensitivity.

Note For research use only.
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  • Anti-Human SRRT IP Recombinant Antibody (SAA0231)

    SDS-PAGE

    SDS-PAGE for Anti-Human SRRT IP Antibody (SAA0231)

References
Formula
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