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Anti-Human ST14 Recombinant Antibody (A11) (HP883023)

Anti-Human ST14 Recombinant Antibody (A11)
Anti-Human ST14 Recombinant Antibody (A11)
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Overview
Catalog No.HP883023
Species reactivityHuman
ApplicationsELISA, IF, in vivo image
Host speciesHuman
IsotypeIgG
Clone IDA11
Clonality Monoclonal
Target Suppressor of tumorigenicity 14 protein, EC:3.4.21.109, Matriptase, Membrane-type serine protease 1, MT-SP1, Prostamin, Serine protease 14, Serine protease TADG-15, Tumor-associated differentially-expressed gene 15 protein, ST14, PRSS14, SNC19, TADG15
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession Q9Y5Y6
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Reconstitution Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Product Usage Information
Application Dilution
ELISA 1:2000-1:20000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Suppressor of tumorigenicity 14 protein (ST14/Matriptase) is a ~94 kDa protein. Exhibits trypsin-like activity as defined by cleavage of synthetic substrates with Arg or Lys as the P1 site. Involved in the terminal differentiation of keratinocytes through prostasin (PRSS8) activation and filaggrin (FLG) processing. Proteolytically cleaves and therefore activates TMPRSS13.

1. Lin, CY. et al. (1999) The Journal of biological chemistry 274, 18231-6. PMID: 10373424
2. Alef, T. et al. (2009) The Journal of investigative dermatology 129, 862-9. PMID: 18843291
3. Murray, AS. et al. (2017) The Journal of biological chemistry 292, 14867-14884. PMID: 28710277
Note For research use only
Images
  • Anti-Human ST14 Recombinant Antibody (A11)

    SDS-PAGE

    SDS-PAGE for Anti-Human ST14 Antibody (A11)

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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