

| Catalog No. | HP883023 | ||||
|---|---|---|---|---|---|
| Species reactivity | Human | ||||
| Applications | ELISA, IF, in vivo image | ||||
| Host species | Human | ||||
| Isotype | IgG | ||||
| Clone ID | A11 | ||||
| Clonality | Monoclonal | ||||
| Target | Suppressor of tumorigenicity 14 protein, EC:3.4.21.109, Matriptase, Membrane-type serine protease 1, MT-SP1, Prostamin, Serine protease 14, Serine protease TADG-15, Tumor-associated differentially-expressed gene 15 protein, ST14, PRSS14, SNC19, TADG15 | ||||
| Endotoxin level | Please contact with the lab for this information. | ||||
| Purity | >95% as determined by SDS-PAGE. | ||||
| Purification | Protein A/G purified from cell culture supernatant. | ||||
| Accession | Q9Y5Y6 | ||||
| Form | Liquid | ||||
| Storage buffer | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. | ||||
| Product Usage Information |
| ||||
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| Background | Suppressor of tumorigenicity 14 protein (ST14/Matriptase) is a ~94 kDa protein. Exhibits trypsin-like activity as defined by cleavage of synthetic substrates with Arg or Lys as the P1 site. Involved in the terminal differentiation of keratinocytes through prostasin (PRSS8) activation and filaggrin (FLG) processing. Proteolytically cleaves and therefore activates TMPRSS13. 1. Lin, CY. et al. (1999) The Journal of biological chemistry 274, 18231-6. PMID: 10373424 2. Alef, T. et al. (2009) The Journal of investigative dermatology 129, 862-9. PMID: 18843291 3. Murray, AS. et al. (2017) The Journal of biological chemistry 292, 14867-14884. PMID: 28710277 | ||||
| Note | For research use only |

SDS-PAGE for Anti-Human ST14 Antibody (A11)
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