Anti-Human STAC3 Polyclonal Antibody (HP344014)

Name: Anti-Human STAC3 Polyclonal Antibody
Brand: abinScience
SKU: HP344014
Price: 168 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HP344014

Species reactivity

Human, Mouse

Applications

ELISA, IHC, WB

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Immunogen

E. coli - derived recombinant Human STAC3 (Ser249-Ile364).

Target

SH3 and cysteine-rich domain-containing protein 3, STAC3

Purification

Purified by antigen affinity column.

Accession

Q96MF2

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

SH3 and cysteine-rich domain-containing protein 3 (STAC3) is a ~41 kDa protein. Required for normal excitation-contraction coupling in skeletal muscle and for normal muscle contraction in response to membrane depolarization. Required for normal Ca(2+) release from the sarcplasmic reticulum, which ultimately leads to muscle contraction. Probably functions via its effects on muscle calcium channels. Increases CACNA1S channel activity, in addition to its role in enhancing the expression of CACNA1S at the cell membrane. Has a redundant role in promoting the expression of the calcium channel CACNA1S at the cell membrane.

1. Horstick, EJ. et al. (2013) Nature communications 4, 1952. PMID: 23736855

2. Wong King Yuen, SM. et al. (2017) Proceedings of the National Academy of Sciences of the United States of America 114, E9520-E9528. PMID: 29078335

Note

For research use only.

Images

References

Datasheet

Anti-Human STAC3 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human STAC3 Polyclonal Antibody (HP344014)

Overview

Images

References

Datasheet

SDS

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